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ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
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Hajime Kataoka

Internal Medicine, Nishida Hospital, Tsuruoka-Nishi-Machi 2-266, Saiki-City, Oita 876-0047

Rationale of the “Chloride Theory” as an Explanation for Neurohormonal Activity in Heart Failure Pathophysiology: Literature Review

We recently proposed a unifying hypothesis of the “chloride theory” for Heart Failure (HF) pathophysiology, which states that changes in the serum chloride concentration are the primary determinant of changes in the plasma volume and neurohormonal activity under worsening HF and its resolution. The proposed hypothesis is based on specul... Read More»

Hajime Kataoka

: J Clin Exp Cardiolog 2019, 10: 634

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article